Featured Cannabinoid of the Week: Cannabichromene (CBC)

by Alexandra Evans, December 15, 2014

cannabichromeneThere are more than 80 different cannabinoids in the cannabis sativa plant, but THC and CBD have gotten the most attention so far. Let’s put the spotlight on another cannabinoid that is just as useful as the other two for medicinal use: cannabichromene (CBC). Cannabichromene is the second most abundant cannabinoid in the marijuana plant, and studies have shown that is contains anti-inflammatory, antibacterial, and anti-fungal activity.

Chemistry and Molecular Structure

CBC is similar to THC and CBD in that they all come from cannabigerolic acid (CBGA). This acid is what many refer to as the “stem cell” of cannabinoids and is a precursor to THC, CBD, and CBC.

Here is an image of the molecular structure of CBC:

Featured Cannabinoid of the Week: Cannabichromene (CBC)

Effects and Medicinal Uses of CBC

I. Anti-Inflammatory

CBC is promising as an anti-inflammatory aid, as shown in a 2012 study published by The British Pharmacological Society. The researchers induced inflammation in a small intestine of a mouse, and then studied the effect of the phytocannabanoid on the animal’s intestinal motility. They drew the conclusion that “CBC selectively reduces inflammation-induced hypermotility in vivo in a manner that is not dependent on cannabinoid receptors or TRPA1.”

Thus, CBC can reduce both swelling and inflammation. Plus, it produces a stronger anti-inflammatory effect when combined with other cannabinoids like THC.

II. Anti-Pain

Since both CBC and CBD are non-psychoactive components of the cannabis sativa plant, both can provide medical benefits without making the patient high. Researchers from a study published in 2011 in The British Pharmacological Society concluded that both CBC and CBD reduce pain “by interacting with several target proteins involved in nociceptive control.”

When combined, CBC and CBD pack a powerful healing punch. “These compounds might represent useful therapeutic agents with multiple mechanisms of action,” wrote the researchers. In this case, two cannabinoids are better than one!

III. Anti-Bacterial and Fungi

In a 1981 study from the University of Mississippi, researchers found that CBC exhibited “strong” antibacterial effects on a variety of gram-positive, gram-negative and acid-fast bacteria – including E. coli and staph (S. aureus). They also found that antifungal activity was mild to moderate.

IV. Cancer

Studies have shown CBC to have anti-proliferative effects, meaning it could inhibit cancerous tumor growth. It works because of anandamide, a breast cancer-fighting endocannabinoid that our bodies produce naturally. CBC inhibits the uptake of anandamide, making it stay in the blood stream for a longer period of time.

The findings from these studies show promise that CBC can help reduce inflammation, bacteria, and fungi within the body. Whether used by itself or in combination with other cannabinoids, CBC is useful as a medicine.

Molecule image source: Wikipedia